The outlook for stroke today has changed thanks to stroke centers capable of performing vessel-opening treatments. Today, nearly 50% of our patients are able to return to an independent life after stroke. But what about the other half?
The brain is a complex and mysterious organ, yet science has gradually begun to better understand the natural biological mechanisms that enable the repair of damaged brain tissue, known as “neuro-repair.” Researchers are also identifying treatment approaches that can support these mechanisms and clarifying the processes collectively referred to as “neuroplasticity,” meaning the processes that enable the recovery of lost functions.
Studies show that the first month following vessel-opening treatments for stroke is the most productive period for neuro-repair and offers important therapeutic opportunities. I refer to the stroke centers of the future as “Hybrid Stroke Centers.” They are “hybrid” because I believe that in the future these centers will provide both vessel-opening treatments and supportive neuro-repair therapies together, early in the course of care, sequentially and without interruption.
The Istinye University Stroke Center (ISUIC) is one of the most established stroke centers in our country, capable of providing all vessel-opening treatments in the early hours after stroke. With nearly 30 years of experience and one of the most comprehensive multidisciplinary teams, it represents a leading institution in stroke care.
November 1, 2024 marks an important milestone for ISUIC. The center has already evolved into what can be considered a stroke center of the future. Within the Istinye University Stroke Center, we established the “Neur-ON Clinic,” where we have implemented new evidence-based “Drug and Cell Therapy Programs” aimed at facilitating the repair of damaged brain tissue after early vessel-opening treatments. Through our “Neuromodulation Platform,” which stimulates the central nervous system using different methods, and our “Motor Rehabilitation Platform,” which enables early intensive neurorehabilitation, we focus on stimulating neuroplasticity at the earliest possible stage. By initiating all these treatments in the earliest phase after stroke—starting within the first 48–72 hours—and implementing them continuously, we have brought together scientifically proven innovative therapies for our patients, even if they may appear different from current standard practices.
As you explore our website, we encourage you to review the information that is important for you. We have provided detailed explanations to help you understand how we aim to design an individualized treatment program for you and your patient.
At Neur-ON Clinic, we have set out with all our knowledge, experience, and partner technologies to achieve meaningful recovery for our patients. Our motto is “Take a step, and let your goals become our mission.” We hope it remains with you.
Prof. Dr. Yakup Krespi


